Extended Data Fig. 6: Effect of intersubunit crosslinking on the CRD conformation.
From: Conformational rearrangement during activation of a metabotropic glutamate receptor
Representative live-cell FRET measurement using HEK293T cells expressing 548UAA with the crosslinking mutation L521C upon application of intermediate (4 µM) and saturating glutamate (1 mM). FRET signal is normalized using initial FRET at time = 0.
