Extended Data Fig. 5: Bazedoxifene prevents ferroptosis in C. elegans.
From: A compendium of kinetic modulatory profiles identifies ferroptosis regulators
a, Representative images of DAPI-stained adult C. elegans under the different treatment conditions indicated below each image. The gonads of fertile worms are indicated (arrows). DGLA: dihomo-γ-linolenic acid (125 µM); Baz: bazedoxifene (150 µM). Scale bar = 100 µm. Imaging was repeated twice and representative animals from one experiment are shown. b, Polyunsaturated fatty acid levels as a function of total lipids determined in worms using gas chromatography/mass spectrometry. Results are from two independent experiments on separate populations of worms.
