Extended Data Fig. 5: Activity of different homologs and a sequence variant of the hovlinc ribozyme. | Nature Chemical Biology

Extended Data Fig. 5: Activity of different homologs and a sequence variant of the hovlinc ribozyme.

From: Hovlinc is a recently evolved class of ribozyme found in human lncRNA

Extended Data Fig. 5

Denaturing PAGE gels with a time course of cleavage reaction for the chimpanzee (a) and bonobo (b) homologs of the hovlinc ribozyme and the human variant containing SNP rs72720496 (c). The cleavage reactions were incubated for the indicated length of time either in the presence of 6 mM Mg2+ or EDTA at pH 8.

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