Extended Data Fig. 4: uPA, uPAR and CDCP1 expression in bioengineered cancer cells.
From: Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
TKCC05 and CAOV3 cells were bioengineered to stably express control ShRNA control (NT), uPA-targeting ShRNA (ShuPA#1 and ShuPA#2) or uPAR-targeting ShRNA (ShuPAR#1 and ShuPAR#2). Gene expression analysis of uPA, uPAR and CDCP1 was performed by RT-qPCR. Results are expressed as mean +/- SD of relative expression compared to ACTB gene expression from three independent experiments. Statistical analysis was performed using One way non-parametric Kruskal-Wallis test with *p=0.0185, #p=0.0325, $p=0.0479, &p=0.0325.
