Extended Data Fig. 3: Evolutionary fitness reconstruction from pooled Sanger sequencing of OrthoRep campaigns.
From: Reconstruction of evolving gene variants and fitness from short sequencing reads
a, Comparison of ground-truth and inferred fitness, indicating a negative epistatic interaction between A-76V and D384Y, S404C in Cry1Ac. b-d, Comparison of MIC values and inferred fitness for evolved PfDHFR variants.
