Extended Data Fig. 4: Chemically induced reconstitution of split proteases.
From: Mandipropamid as a chemical inducer of proximity for in vivo applications
a, Schematic illustration of CIP induced reconstitution of TEV protease followed by proteolytic activation of cyclic Luciferase. b, Normalized enhancement of cLuc activity induced by proteolytic activation at different Mandi concentrations. Box extends from 25th to 75th percentiles, whiskers from min to max, bar represents median. Conditions were compared using two-sided unpaired t-test with Welch’s correction. Representative data from one experiment of two independent experiments.
