Extended Data Fig. 4: Comparison of glycan affinities for RBD measured by ESI-MS and their relative abundances measured by CaR-ESI-MS screening.
From: Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2
Comparison of glycan (15, 21, 27, 35, 36, 69, 71, 76 and 129) affinities for RBD measured by ESI-MS and their relative abundances measured by CaR-ESI-MS screening (performed at 25 °C). Black bars represent the ratio of the abundance of released glycans normalized to that of 71 under same conditions. White bars represent the ratios of dissociation affinities of RBD against 69 to dissociation affinities of RBD against glycan (L). ND, not detected. For relative abundances by CaR-ESI-MS, data represent ± s.d., n = 3 independent experiments. For Kd values, means ± s.d., n = 3 independent experiments for each glycan concentration.
