Extended Data Fig. 3: Zero-charge mass spectrum for an aqueous ammonium acetate solution of SARS-CoV-2 RBD. | Nature Chemical Biology

Extended Data Fig. 3: Zero-charge mass spectrum for an aqueous ammonium acetate solution of SARS-CoV-2 RBD.

From: Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2

Extended Data Fig. 3

a, Zero-charge mass spectrum of RBD acquired in positive ion mode with a UHMR Orbitrap mass spectrometer for an aqueous ammonium acetate (100 mM, pH 6.9) solution of SARS-CoV-2 RBD (10 μM). Deconvolution was performed using the Thermo BioPharma Finder SoftwareTM. The glycan composition of each species is indicated (N ≡ HexNAc, H ≡ Hex, F ≡ Fuc, S ≡ Neu5Ac). b, Heatmap showing the distribution of the number of Neu5Ac and Fuc residues in the RBD glycoforms.

Back to article page