Extended Data Fig. 4: Representative density map of S1PR1/Gi complexes and 3D variability analysis. | Nature Chemical Biology

Extended Data Fig. 4: Representative density map of S1PR1/Gi complexes and 3D variability analysis.

From: Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism

Extended Data Fig. 4

a-c, The cryo-EM density map of the representative regions of the S1PR1/Gi complexes. The density map is drawn by pymol at the contour level of 3.0. d, Representative image of the 3D variability analysis of the S1PR1 cryo-EM maps. The yellow arrow marks the position of ligand and the red arrow marks TM1.

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