Extended Data Fig. 3: Genetic alterations of CRC organoids.
From: Organoid screening reveals epigenetic vulnerabilities in human colorectal cancer
Genetic mutations in CRC organoids used for HTS (top). Mutations in recurrently mutated genes in CRC (MutSigCV FDR < 0.2 in Pan-Cancer Atlas30) are shown. Chromosomal copy number variations in CRC organoids (bottom). Chromosome states are shown as the log2 ratio of the copy number between the sample and euploid genome.
