Extended Data Fig. 4: LRP8 promotes ferroptosis resistance in multiple cancer cell lines.
From: Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
a, Validation of LRP8KO in multiple cancer cell lines. Westen blot of pools of LRP8KO cells generated from two different sgRNAs and control Cas9-expressing cells. b-d, Time-lapse cell death analysis of U87-MG (b), A375 (c), and SK-MEL28 (d) cells treated with RSL3 over 24 hr or 72 hr. Data represent mean ± S.E.M. of three replicates.
