Extended Data Fig. 8: Enrichment analysis for the upregulated metabolites and differentially expressed genes in the single-cell RNA-Seq data. | Nature Chemical Biology

Extended Data Fig. 8: Enrichment analysis for the upregulated metabolites and differentially expressed genes in the single-cell RNA-Seq data.

From: MNK2 deficiency potentiates β-cell regeneration via translational regulation

Extended Data Fig. 8

a, Pathway analysis, assessing 81 characterized metabolic pathways in zebrafish, using the significantly upregulated metabolites. Only pyrimidine metabolism was significantly enriched in this dataset (FDR < 0.05). b, Enrichment analysis for KEGG pathways in differentially expressed genes, that is, genes upregulated in ductal cells (‘low-notch’ cluster, see Fig. 2g) compared to all endocrine cells.

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