Extended Data Fig. 7: Monomeric and higher oligomeric states lead to inefficient virus neutralization.
From: A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein
a, Sedimentation-velocity analytical ultracentrifugation data of SIH-11, SIH-13, SIH-14, and SIH-15. *OS – oligomeric state. b, Pseudovirus neutralization assay. Data represents the average and standard deviation of replicates (n = 2). The data for LCB1 and SIH-5 from Fig. 4 are replicated for better comparison. All pseudoviral assays were repeated thrice. c, Kinetics of the pseudoviral infection in the presence of SIH-11. Data represents the average and standard deviation of replicates (n = 2). All pseudoviral assays were repeated thrice.
