Extended Data Fig. 5: Chemical reactivity of tethers to DMS in whole polysomes.
From: Three-dimensional structure-guided evolution of a ribosome with tethered subunits
Targeted structure probing was performed on the tethers of both RiboTv2 and RiboTv3 polysomes via DMS-MaPseq. The per-nucleotide chemical reactivities of the tethers and their adjacent rRNA stems can be seen in the figure for both RiboTv2 (a) and RiboTv3 (b). Gray shaded nucleotides represent U and G residues that are not modified by DMS.
