Extended Data Fig. 5: Co-crystal structure of the K-Ras(G12S)•GDP•G12Si-5 adduct.
From: Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)
a) Co-crystal structure of the K-Ras(G12S)•GDP•G12Si-5 adduct. b) Superimposed conformations of G12Si-1 and G12Si-5 in their respective co-crystal structures with K-Ras(G12S)•GDP. For X-ray crystallography data collection and refinement statistics, see Supplementary Table 1.
