Extended Data Fig. 9: A working model for SEU during osmotic response.
From: Condensation of SEUSS promotes hyperosmotic stress tolerance in Arabidopsis
Under normal growth condition, SEU is diffused in the nucleus. When cells encounter hyperosmotic stress, shrinkage of cell volume leads to an increase of macromolecular crowding inside cells. Due to the hypersensitivity to crowding, IDR1 adopts more compact conformation, leading to the increase of local concentration and subsequent phase separation of SEU. Phase-separated SEU promotes the expression of stress-tolerance genes, thereby support cell survival.
