Extended Data Fig. 2: Dose response of sentinel strains to target DNA concentration.
From: Sentinel cells programmed to respond to environmental DNA including human sequences
Sentinel cells were incubated with plasmid DNA containing the target sequence with either the reference SNP allele (SEQ2, SEQ3, SEQ4, SEQ5) or an alternate SNP allele (SEQ2C, SEQ3G, SEQ4G, SEQ4T, SEQ5A). The recording frequencies were calculated from the flow cytometry data shown in Supplementary Fig. 1 and data were fit to Eq. 1. c0 is unitless and κ has units of pM. The grey data points are for the cells incubated without DNA and the dashed line indicates the average DNA uptake frequency calculated across all –DNA data points. The data show three replicates performed on different days.
