Fig. 2: Iridophores use a unique molecular machinery to facilitate guanine production and crystal formation.
From: Genetic control over biogenic crystal morphogenesis in zebrafish
a, Illustration of an iridophore packed with iridosomes (membrane-bound crystals); different organelles are color-coded. Insets in grayscale show high-resolution Cryo-electron tomography images of iridosomes. b, Volcano plot displaying differentially expressed proteins between iridophores (n = 3) and a control, heterogenous cell population (n = 3) in zebrafish larvae at 5 dpf (P = 0.01 and fold change (FC) > 2). Upregulated proteins are shown in blue and downregulated proteins are shown in pink. c, Bar graph depicting the elevated expression of key iridophore marker proteins. d, GO enrichment analysis highlighting upregulated (purple) and downregulated biological processes (pink) for identified proteins using a modified Fisher’s extract test from STRING41.
