Extended Data Fig. 7: All-in-one constructs of mini RESCUE-S mediated endogenous mRNA base editing.
From: Compact RNA editors with natural miniature Cas13j nucleases
a. A-to-G editing efficiency among RESCUE-S, Chi-RESCUE-S, Chi-RESCUE-S-mini3, RESCUE-S-X.1 and RESCUE-S-t1. p < 0.05 was considered to be statistically significant. b. C-to-U editing efficiency among RESCUE-S, Chi-RESCUE-S, Chi-RESCUE-S-mini3, RESCUE-S-X.1 and RESCUE-S-t1. p < 0.05 was considered to be statistically significant. All values shown are mean ± s.e.m. (left n = 3 biological replicates, each average of 3 technical replicates, right n = 20). Statistical significance was assessed using two-tailed t-tests compared to RESCUE-S.
