Extended Data Fig. 1: Autophagy activation upon PEI treatment.
From: Chemically engineered antibodies for autophagy-based receptor degradation
a, The corresponding quantifications of confocal images in Fig. 1c–h and Fig. 1j (Fig. 1c, n = 10 cells; Fig. 1d, n = 12 cells; Fig. 1e, n = 15 cells; Fig. 1f, n = 15 cells; Fig. 1g, n = 12 cells; Fig. 1h, n = 10 cells; Fig. 1j, n = 15 cells, means ± s.d.; Quantification is unnecessary for the untreated group due to the absence of PEI signal in cell.). b,c, Representative images and relative quantifications of mCherry-LC3B (b) or mCherry-LC3C (c) stably expressing HeLa cells upon treatment with 1 μM of L25K PEI for indicated period of times. The quantifications are shown on the right (n = 15 cells per group, means ± s.d.). DNA in b and c was counterstained with DAPI. Scale bars, 10 μm.
