Extended Data Fig. 3: Editing performance of A > I snRNAs with U7 versus U1 snRNA promoter/terminator cassette.
From: Enhancing RNA base editing on mammalian transcripts with small nuclear RNAs
Editing percent performance by transfection in HEK293T cells of A > I snRNAs targeting three different genes and driven by either U7 or U1 snRNA promoter/terminator cassette. Overperformance significance versus U7 promoter: **, ***: p < 1e-2, 1e-3 (one-way ANOVA) (GAPDH 0.0023, TARDBP 6e-4). Error bars reflect standard error of mean. n = 3 biological replicates per condition.
