Supplementary Figure 1: Repopulation of microglia by peripheral myeloid cells in chimeric Cx3cr1CreER/+R26DTR/+ and Cx3cr1CreER/+R26DTA/+ mice. | Nature Immunology

Supplementary Figure 1: Repopulation of microglia by peripheral myeloid cells in chimeric Cx3cr1CreER/+R26DTR/+ and Cx3cr1CreER/+R26DTA/+ mice.

From: Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling

Supplementary Figure 1

(a) Gating strategy of CNS cells employed in the study. (b-c) Analysis of CNS, top panel gated on live, singlet and Ly6C–Ly6G– cells in (b) CD45.1→Cx3cr1CreER/+R26DTR/+ and (c) CD45.1→Cx3cr1CreER/+R26DTA/+ chimeras. Values in dot plots are mean±s.d. of (b) n=5 and 6 mice from two pooled experiments and (c) n=5 mice/group from one of two independent experiments.

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