Supplementary Figure 3: MS4A4A transcript levels in human tumors and its correlation with TAM markers. | Nature Immunology

Supplementary Figure 3: MS4A4A transcript levels in human tumors and its correlation with TAM markers.

From: The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis

Supplementary Figure 3

a) Boxplot of MS4A4A mRNA expression in human tumors (closed boxes) and corresponding normal tissues (open boxes) among different TCGA cancer datasets. b) Heatmap correlation between mRNAs encoding MS4A4A and TAM markers in tumor tissues among different TCGA cancer datasets. Genes are represented according to their average Pearson correlation with MS4A4A among all cancer datasets. Number of samples included in the analysis of both panels (normal tissue, corresponding tumor tissue) are: bladder urothelial cancer: 19, 408; breast cancer: 112, 1100; cervical adenocarcinoma: 3, 306; cholangiocarcinoma: 9, 36; colon adenocarcinoma: 41, 287; colorectal adenocarcinoma: 51, 382; esophageal cancer: 11, 185; esophageal carcinoma: 46, 600; glioblastoma: 5, 166; glioma: 5, 696; head and neck cancer: 44, 522; kidney cancer: 25, 66; kidney clear cell cancer: 72, 534; kidney renal papillary cell cancer: 32, 291; liver cancer: 50, 373; lung cancer: 59, 517; lung squamous cell cancer: 51, 501; pan-kidney cohort: 129, 891; pancreatic cancer: 4, 179; paraganglioma: 3, 184; prostate cancer: 52, 498; rectum cancer: 10, 95; sarcoma: 2, 263; stomach adenocarcinoma: 35, 415; thymoma: 2, 120; thyroid cancer: 59, 509; uterine cancer: 24, 177.

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