Supplementary Figure 6: The ABC signature is enriched in both SLE and HC DN2 B cells.
From: Epigenetic programming underpins B cell dysfunction in human SLE
GSEA of the comparing the HC DN2 versus HC SM (top), SLE DN2 versus SLE SM (middle), or SLE DN2 versus HC DN2 (bottom) for enrichment with ABC datasets. Gene set comparing (a) ABC versus young follicular B cells (FoB)2, (b) ABC versus old FoB2, and (c) old ABC versus old FoB3. FDR < 0.05 was considered significant using the Benjamini-Hochberg correction on the P-value derived from permutation testing.
