Supplementary Figure 2: Sequencing and QC of B cell subsets.
From: Epigenetic programming underpins B cell dysfunction in human SLE
(a) Schematic and workflow of cell isolation and processing. (b) Annotation of data sets collected for each subject and cell type for each of the three genomic assays performed. (c) Bar plot showing the conversion efficiency of methylated and unmethylated DNA methylation libraries. (d) Representative histogram showing distance between paired-end reads for ATAC-seq data from one experiment. Similar results were obtained from all ATAC-seq samples. (e) Density plots of transcript expression for all RNA-seq libraries with the detection threshold annotated.
