Supplementary Figure 5: Depletion of PD-1+CD38hi CD8+ T cells results in strong anti-tumor response. | Nature Immunology

Supplementary Figure 5: Depletion of PD-1+CD38hi CD8+ T cells results in strong anti-tumor response.

From: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

Supplementary Figure 5

a. Tumor growth of variously treated B16-bearing Rag1–/– mice following transfer of either total or PD-1+CD38+ depleted, in vitro activated CD8+ T cells (with an indicated number of mice per group given in parentheses). b. The full scan of the blot showing the expression of CD38 and β-actin in flow-sorted PD-1+CD38+ T cells transfected either with scrambled RNA (scRNA) or CD38 siRNA.

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