Supplementary Figure 4: ZIKV-neutralizing activities of WT C57BI/6J mice immunized with ZIKV E-monomer and E-dimer proteins. | Nature Immunology

Supplementary Figure 4: ZIKV-neutralizing activities of WT C57BI/6J mice immunized with ZIKV E-monomer and E-dimer proteins.

From: A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection

Supplementary Figure 4

WT C57BI/6J were immunized and boosted with ZIKV E-monomer, ZIKV E-dimer or CHIKV E2 proteins using Addavax as adjuvant. Neutralizing potential of the serum was determined by FRNTs and individual mouse neutralization curves are shown. n=25 animals per group. Each point represents the mean of two technical replicates with error bars denoting the range, each graph shows the results of 5 individual animals.

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