Fig. 4: The relationship between anti-SARS-CoV-2 neutralizing activity and time post-symptom onset.
a, The levels of neutralization activity were plotted against the time post-symptom onset for those individuals who were symptomatic either for COVID-19 or MIS-C. The adult groups (CPD, open black squares, n = 19 and COVID-ARDS, closed red squares, n = 13) are plotted on the left and the pediatric groups (MIS-C, closed green circles, n = 16 and non-MIS-C, open blue circles, n = 16) are plotted on the right with the best fit line and P value calculated using simple linear regression (COVID-ARDS: R2 = 0.36, slope = 0.040, y-intercept = 1.34). b, The anti-S IgG levels (left) and neutralizing activity (right) of MIS-C individuals (n = 10) during the acute phase of illness and at a follow-up visit 2–4 weeks after hospital discharge. The P values were calculated using a two-way paired t-test.
