Extended Data Fig. 4: Thymic γδ17 cells are increased upon inhibition of glucose uptake. | Nature Immunology

Extended Data Fig. 4: Thymic γδ17 cells are increased upon inhibition of glucose uptake.

From: Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

Extended Data Fig. 4

Flow cytometry profiles of thymic γδTN (CD44-CD45RB-), γδ17 (CD44+CD45RB-) and γδIFN (CD44+CD45RB+) cells in γδ24- cells from E15 thymic lobes in 7-day FTOC with media containing or not Fasentin. Histograms show the number of γδ17 T cells (p<0.0001) and γδ17/γδIFN ratio (p=0.0028). Data are representative of 2 independent experiments (at least 4 lobes pooled per group per experiment). Error bars show mean±SEM, **p < 0.01, ****p < 0.0001, using two-tailed unpaired Student’s t-test.

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