Extended Data Fig. 8: Inhibition of dietary fat uptake reduces tumour growth and γδ17 cells in the tumour. | Nature Immunology

Extended Data Fig. 8: Inhibition of dietary fat uptake reduces tumour growth and γδ17 cells in the tumour.

From: Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

Extended Data Fig. 8

B16F10-tumour bearing mice were given daily injections of either vehicle or orlistat on days 6-9, and tumours were analysed on day 10. a, Percentage body weight following tumor cell injection; arrows indicate when orlistat or vehicle were administered. b, Tumor volume on days 8-10 following B16F10 inoculation. Absolute numbers c, and LipidTOX staining d, of tumor-infiltrating γδ17 cells on day 10. n=8 biologically independent animals, data from 1 independent experiment. Data represents mean+SD, *p<0.06, **p < 0.01 using unpaired Student’s t-test or one-way ANOVA.

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