Extended Data Fig. 6.: Transplantation of HSCs from Ebf1-deficient niche to wild-type recipients.
From: EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential
a, Percent of chimerism in peripheral blood (PB) during the course of experiment. Percentage of CD45.2+ donor-derived cells in PB within myeloid cells (Mac1+) b, B cells (CD19+) c, and T cells (CD3+) d over time. Data represent the mean ± s.e.m with n=18 recipients of HSCs from Ebf1+/+Prx1Cre mice and n=18 recipients of HSCs from Ebf1fl/flPrx1Cre mice in the primary bone marrow transplantation and n=20 recipients of HSCs from Ebf1+/+Prx1Cre mice and n=29 recipients of HSCs from Ebf1fl/flPrx1Cre mice in the secondary bone marrow transplantation.
