Extended Data Fig. 5: CD8-MP TCRrg cells are broadly distributed across lymphoid sites.
From: Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells
Summary plots of the frequency of Thy1.1 expressing TCRrg cells of TCRβ+ CD8β+ T cells, normalized to the spleen from the indicated lymphoid sites 6–7 weeks after bone marrow reconstitution of the indicated “low frequency” TCRrg mice. Frequencies at different lymphoid sites were normalized to the spleen to control for varying engraftment of TCRrg bone marrow across different mice. iabLN: inguinal, axial, brachial lymph nodes; cLN: cervical lymph nodes; mLN: mesenteric lymph nodes; pLN: periaortic lymph nodes. Each symbol represents an individual TCRrg mouse. n = 3, GSSrg; n = 4, DTGrg; n = 4, SAVrg; n = 3, SATrg; n = 4, SMNrg; n = 3, RDTrg; n = 4, LNNrg; n = 4, DYQrg. Mean ± SEM is indicated. Data is pooled from four independent experiments.
