Extended Data Fig. 7: Single cell RNAseq analysis of lung-resident ILC2s.
From: Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition
a, Uniform Manifold Approximation and Projection (UMAP) plot illustrating defined clusters of cells generated by single cell RNA-sequencing of lung-resident live ILC2 populations (CD45+Lin-CD90+CD127+) sort-purified from control (and basophil-depleted (baso-dep) mice 5 days post-Nb infection. b, Top 10 marker genes expressed by each cluster of ILC2s. c, Single-cell expression of Il5, Il13, Areg, Arg1, Il1rl1, and Il17rb in ILC cell clusters as defined in A. Horizontal bars represent mean normalized expression. P values were determined by Wilcoxon signed rank sum test. *P < 0.05, **P < 0.01, ***P < 0.001.
