Fig. 1: Immune cell frequencies and status in the blood of patients with COVID-19.
From: Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity
a,b, Whole blood or PBMCs were collected from patients and analyzed through flow cytometry. Flow cytometry analysis of CD3+ cell (a), αβ T cell and γδ T cell frequencies (b) from uninfected controls (n = 80), patients with COVID-19 hospitalized in an IDU (n = 62) or ICU (n = 66). c, Flow cytometry analysis of CD4+ T cell, regulatory T cell (Treg) and CD8+ T cell frequencies in the blood of patients as described in a and b. d,e, Representative quantile contour plots of Vα7.2 and CD161 staining to identify MAIT cells in the blood of uninfected controls and patients with COVID-19 from IDU and ICU, and MAIT cell (d) and CD8+ MAIT cell (e) frequencies in the blood of patients as described in a and b. SSC, side scatter. Small horizontal lines indicate the median and quartiles. Each symbol represents one biological sample. *P < 0.05, **P < 0.01 and ****P < 0.0001 (two-sided Mann–Whitney non-parametric test).
