Extended Data Fig. 2: MAIT cells co-staining with MR1-Tetramer and Vα7.2+ CD161+.
From: Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity
a, Flow cytometry analysis of 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil (5-OP-RU)-loaded MR1 tetramer binding among Vα7.2+ CD161+ MAIT cells in uninfected patients (n = 11) and SARS-CoV-2 infected patients from Infectious Disease Unit (IDU) (n = 11) and Intensive Care Unit (ICU) (n = 13). b, Dot plot representative of MR1-Tetramer+ CD161+ MAIT cells in one uninfected control and one COVID-19 patient from IDU and one from ICU. c, Dot plot representative of CD161+ Vα7.2+ Tetramer MR1+ GzB+ in PBMC and (Bronchoalveolar lavage) BAL from one ICU patients.
