Extended Data Fig. 6: MAIT cell functions are impacted in fatal SARS-CoV-2 infection. | Nature Immunology

Extended Data Fig. 6: MAIT cell functions are impacted in fatal SARS-CoV-2 infection.

From: Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity

Extended Data Fig. 6

a, Flow cytometry analysis of IFNγ, TNF, IL-2, IL-4, IL-10, IL-17, and granzyme B production among stimulated MAIT cells (n = 22), conventional CD8+ and CD4+ T cells, γδT and CD3 cells in non-fatal (n = 23) versus fatal COVID-19 patients (n = 6). b, Flow cytometry analysis of granzyme B among unstimulated MAIT cells, conventional CD8+ and CD4+ T cells, γδT and CD3 cells in non-fatal (n = 16) versus fatal COVID-19 patients (n = 5). Each symbol represents a single patient. *P < 0.05 and **P < 0.01 (two-sided Mann-Whitney nonparametric test).

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