Fig. 5: The magnitude of the T cell response at 6 months correlates with peak antibody level.
From: Robust SARS-CoV-2-specific T cell immunity is maintained at 6 months following primary infection
a, Antibody levels against spike (n = 81), nucleoprotein (n = 94) and RBD (n = 87) of all patients at each time point after infection were plotted. Each gray line represents an individual patient. The median antibody (Ab) level over time is shown in red. b, The correlation of ELISPOT responses at 6 months against peak antibody levels (spike, n = 82; nucleoprotein, n = 94 and RBD, n = 87) were assessed for each antibody. c, Correlation of ELISPOT responses at 6 months with rate of antibody decline (expressed as ratio of antibody level at 2 months after peak level to antibody peak level) (spike, n = 60; nucleoprotein, n = 79 and RBD, n = 67). The line represents linear regression. Spearman’s rank correlation (two-sided) was used to test the significance and P value and r value (correlation coefficient) are indicated in each panel.
