Extended Data Fig. 3: Single cell analysis identifies unique human WAT-resident ILCs. | Nature Immunology

Extended Data Fig. 3: Single cell analysis identifies unique human WAT-resident ILCs.

From: Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

Extended Data Fig. 3

a, Representative sorting strategy for Lin–CD7+ cell populations based on expression of CD200R1; used in Fig. 2. b, Unsupervised heatmap of the top 5 differentially expressed cluster marker genes for each indicated innate lymphoid cell cluster. Cluster identities are shown above the heatmap. Color saturation indicates the strength of expression. c, Selected UMAP feature plots showing RNA expression of additional cluster markers, based on the UMAP shown in Fig. 2a. d, UMAP of sorted innate lymphoid cell populations denoted by the source of the sorted sample (CD200R1+ vs CD200R1–) and patient source classification as lean (red, green) or obese (blue, purple); based on the UMAP shown in Fig. 2a. e, Bar plots showing the proportion of innate lymphoid cells derived from 7 lean (blue) and 5 obese (red) patients.

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