Extended Data Fig. 2: HCV-epitope sequences and identification of functional escape mutations. | Nature Immunology

Extended Data Fig. 2: HCV-epitope sequences and identification of functional escape mutations.

From: Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

Extended Data Fig. 2

a, Sequences of select HCV epitopes across patients included in this study. Escape mutations are written in red and T cell status, whether the cells have full recognition of the virus (TEX) or are partially (TP-ESC) or fully escaped (TF-ESC) is indicated as determined through functional assays of the recognition of the variant epitopes compared to wild-types by intracellular cytokine detection of IFNγ by flow-cytometry (b).

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