Extended Data Fig. 8: Relationship of Cytokine/chemokine levels with SARS-CoV-2 clinical disease score.
From: SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19
Correlation and linear regression of cytokine/chemokine levels (log10 concentration) for serum sample from each patient were evaluated with corresponding maximum pediatric Sequential Organ Failure Assessment (pSOFA) score for each SARS-CoV-2 infected child on all the days post-enrollment, regardless of disease severity. Each dot represents a unique patient and associated pSOFA score; orange, Mild/moderate COVID-19 (n = 20); red, Severe COVID-19 (n = 15); cyan, Mild/moderate MIS-C (n = 8); blue, Severe MIS-C (n = 17). The linear regression were performed across all SARS-CoV-2 infected children. Black line indicates the regression line for all patients. Associated Pearson’s correlation coefficients (r) and linear regression significance (p) are shown. The trend line is depicted as solid black line with the error bands representing 95% confidence interval shown as shaded area.
