Extended Data Fig. 2: Plasma IgG1 and IgA titers from the attenuated Mtb (Mtb-ΔsigH) vaccination cohort.

Fold change in a, IgG1 and b, IgA titers present in the plasma of each rhesus macaque following vaccination. Fold changes were calculated as fold change in Luminex MFI over the pre-vaccination level for each macaque. Each point represents the duplicate average from a single macaque. Mtb challenge was performed week 8 post-vaccination. Two-tailed Mann-Whitney U tests were performed on the fold change values at each timepoint, comparing the Mtb-ΔsigH to the BCG group. P-values < 0.05 are shown.