Extended Data Fig. 3: Algorithm comparison and amplitude assessment for rhythmic transcripts.
From: Aging disrupts circadian gene regulation and function in macrophages
a. Venn diagrams of unique and shared rhythmically expressed transcripts in young vs. aged macrophages, compared across different algorithms (JTK_CYCLE, RAIN, BooteJTK, and MetaCycle) and q-values. b. JTK_CYCLE amplitudes of genes in peritoneal macrophages from young and aged mice. Genes are binned by their rhythmicity in neither, both, or individual groups. n = 21 mice in each age group and n = 3 in each time group. Boxes extend from the 25th-75th percentiles, whiskers extend to 1.5 times the IQR, and the center line is the median.
