Extended Data Fig. 4: No aberrant metabolic profiles in mTORC2-deficient memory CD4+ T cells. | Nature Immunology

Extended Data Fig. 4: No aberrant metabolic profiles in mTORC2-deficient memory CD4+ T cells.

From: The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis

Extended Data Fig. 4

a, b, Profile of (a) extracellular acidification rate (ECAR) and (b) oxygen consumption rate (OCR) of sorted memory CD4+ T cells (CD25−GITR−CD44highCD4+) from either CD4Cre-Rictorfl/fl (Rictor−/−, red) or Rictorfl/fl (blue) mice at day 60 post infection of LCMV Arm+ (n=3 biological replicates, pooled from at least 20 mice in CD4Cre-Rictorfl/fl group and 10 mice in Rictorfl/fl group). The presented data are representative of two independent experiments. Data are presented as mean values ± SD and analyzed by unpaired two-tailed t-test in a-b.

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