Extended Data Fig. 9: TDB administration induces IL-1β expression in splenic myeloid cells in vivo.
From: IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines
a, b, Gating strategy (a) and expression of pro-IL-1β (b) in spleen cell subsets following vehicle (n = 8) or TDB administration (n = 10) in ID8/LyPD1 tumor-bearing mice. The data are pooled from two independent experiments with biologically independent samples. Significance was determined using unpaired two-tailed Student’s t-test. Horizontal bars indicate median.
