Extended Data Fig. 8: NLRP11 does not affect TGN localization of NLRP3. | Nature Immunology

Extended Data Fig. 8: NLRP11 does not affect TGN localization of NLRP3.

From: NLRP3 licenses NLRP11 for inflammasome activation in human macrophages

Extended Data Fig. 8

(a,b) Confocal microscopy of PMA-differentiated Cas9Ctrl, NLRP11KO and NLRP3KO cells left untreated, primed with Pam3CSK4 (1 μg ml−1, 2 h) or primed+activated with Nig (5 μM, 20 min) immunostained for (a) Tom20 (green), NLRP3 (red) and DAPI (blue), and (b) TGN46 (green), NLRP3 (red) an d DAPI (blue).

Back to article page