Extended Data Fig. 4: Stress granule assembly is involved in IL-33 transportation under allergen protease stimulation. | Nature Immunology

Extended Data Fig. 4: Stress granule assembly is involved in IL-33 transportation under allergen protease stimulation.

From: Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion

Extended Data Fig. 4

a, Venn diagrams of mass spectrometry analyzed IL-33 interactome from HEK293T cells expressed with C-terminal HA-tagged human IL-33 following the treatment of Ctrl (without stimulations), Pap (10 µg/mL papain for 30 min), and AS (0.5 mM arsenite exposure for 1 h). b, Venn diagrams of proteins with up-regulated interaction with IL-33 under papain and AS stimulation as in a. c, Common proteins associated with non-membrane-bounded organelle assembly were observed with up-regulated interaction with IL-33 as in a. d, Metascape analyzed protein clusters enriched with IL-33 under papain (10 µg/mL for 30 min) exposure context.

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