Extended Data Fig. 3: Conduits are stretched in the swelling lymph node. | Nature Immunology

Extended Data Fig. 3: Conduits are stretched in the swelling lymph node.

From: Multitier mechanics control stromal adaptations in the swelling lymph node

Extended Data Fig. 3

(a) Schematic illustration of the conduit unit from the T-zone. (b) Example of a decellularized homeostatic (day 0) popliteal lymph node (LN). (c) Conduit imaged by scanning transmissive electron microscopy (STEM) in which the characteristic D-period of collagen fibrils can be observed. Scale bar = 500 nm. (d) Examples of a T-zone conduit at different tilting angles acquired by STEM tomography. Scale bar = 500 nm. (e) Schematic of computed weight back projection to reconstruct a 3D volume of a conduit from differential tilting angles.

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