Extended Data Fig. 4: Impact of the microbiota on ILC3 patrolling.
From: Inflammation triggers ILC3 patrolling of the intestinal barrier
a, Representative intravital images of ILC3s (scale bar 50 µm) in intestinal villi Abx-treated RR22 mice (2 weeks after treatment) from one of three independent experiments. b, Individuals tracks of intestinal Il22− and Il22+ ILC3s in treated RR22 mice. c, Graphs show mean speed, arrest coefficient and straightness ratio of indicated populations in RR22 and RR22 + Abx mice. Results are from one to three movies per condition from one of three independent experiments (n = 257 and n = 341 for Il22− and Il22+ ILC3s in RR22 mice, respectively; n = 124 and n = 134 Il22− and Il22+ ILC3s in RR22 + Abx mice, respectively). Each bar corresponds to the mean ± s.e.m of the values obtained (ns, not significant; ***P < 0.001; one-way ANOVA; exact P values are provided in the source data). RR22, Rag2−/−RorcGFPIl22TdT; Abx, antibiotics.
