Extended Data Fig. 7: Jmjd1c did not regulate H3K9 methylation in B cells.
From: Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis
a, B cells were sorted from Jmjd1c+/+ Mb1Cre+ and Jmjd1cfl/fl Mb1Cre+ mice. The level of Jmjd1c and H3K9me was subsequently analyzed by western blot. Blots were probed against Jmjd1c, β-actin, H3K9me1, H3K9me2, H3K9me3 and total H3. Data are representative of 2 individual experiments. b, Anti-H3K9me2 CUT&Tag was performed with B cells from Jmjd1c+/+ Mb1Cre+ and Jmjd1cfl/fl Mb1Cre+ mice to analyze the genomic distribution of H3K9me2 modification. The overall H3K9me2 peak signal was shown in averaged profile plot (left) or heatmap (right).
