Extended Data Fig. 9: Jmjd1c expression in B cells suppressed lupus-like disease.
From: Jmjd1c demethylates STAT3 to restrain plasma cell differentiation and rheumatoid arthritis
a and b, Jmjd1c+/+ Mb1Cre+, Jmjd1cfl/fl Mb1Cre+ and Jmjd1cOEMb1Cre+ mice were intraperitoneally injected with 7.5 million of CD4+ T cell from C57BL/6 mice (control) or from bm12 mice. a,ELISA of anti-dsDNA in serum from immunized mice at day 14. b, Representative immunofluorescent images showing IgG deposits in kidney by staining with Cy3-labeled anti-mouse IgG. Scale bar, 50 μm. Data are means ± SEM. Student’s t tests were used (NS, not significant, *p < 0.05, **p < 0.01, ***p < 0.001). Data are pooled from 2 experiments.
